Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry
نویسندگان
چکیده
منابع مشابه
Differential quantification of isobaric phosphopeptides using data-independent acquisition mass spectrometry.
Phosphorylation is a post-translational modification (PTM) fundamental for processes such as signal transduction and enzyme activity. We propose to apply data-independent acquisition (DIA) using mass spectrometry (MS) to determine unexplored phosphorylation events on isobarically modified peptides. Such peptides are commonly not quantitatively discriminated in phosphoproteomics due to their ide...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-018-07454-w